GoSurfer was updated at 12/11/2006 Platforms: Windows 2000/XP     GoSurfer uses Gene Ontology (GO) information to analyze gene sets obtained from genome-wide computations or microarray analyses. GoSurfer is a graphical interactive data mining tool. It associates user input genes with GO terms and visualizes such GO terms as a hierarchical tree. Users can manipulate the tree output by various means, like setting heuristic thresholds or using statistical tests. Significantly important GO terms resulted from a statistical test can be highlighted. All related information are exportable either as texts or as graphics.

News & Updates:
 

12/11/2006: New version of GoSurfer is released which can process multiple gene groups.

04/05/2006: GoSurfer is cited by A Primer of Genome Science, published by Sinauer Associates, Inc.


03/03/2006: GO structure file is updated. Some new Gene Information Files are added.

06/30/2005: GoSurfer is rated as "the fastest Gene Ontology analysis tool" by Purvesh Khatri and Sorin Draghici's review article in Bioinformatics.

04/29/2004: A short tutorial is available. It can also be activated in the GoSurfer program by using the "Help->Online Tutorial" menu.

03/20/2004: The false discovery rate (FDR) for GO-term to gene-list association test can be calculated from menu "Analysis->FDR". Users can highlight the GO terms with small FDRs (q-values) from menu "Analysis->Highlight->Significance test: adjusting for multiple hypothesis testing".

Reference:

Zhong S, Storch F, Lipan O, Kao MJ, Weitz C, Wong WH. GoSurfer:  a graphical interactive tool for comparative analysis of large gene sets in Gene Ontology space. Applied Bioinformatics 2004, 3(4): 1-5. Abstract, Technical report

For questions and suggestions, please contact:
Sheng Zhong, Dept of Bioengineering, University of Illinois and Urbana-Champaign
 

This site was last updated 12/11/06